People with a uterus must use both estrogen and progesterone to avoid thickening of the lining of the womb that can lead to endometriosis. “Over the years, however, the therapies have changed a lot, both in terms of type of drugs and dosages, and therefore the side effects of today’s therapy may be quite different from those of HRT from back then,” she said in a statement.
However, the study only looked at people who used a certain type of HRT - a combination of estrogen and progestin that was widely prescribed at that time, said Andrea Lenzi, a professor of endocrinology at the University of Rome La Sapienza, who was not involved in the study. Menopause symptoms cost billions in medical expenses and lost days of work, study suggests (add caption) Krisanapong Detraphiphat/Moment RF/Getty Images Researchers compared people with dementia who had used hormone therapy, even briefly, with those from the larger group who had not. Over 5,500 of those women were later diagnosed with dementia or Alzheimer’s disease. The new study, published Wednesday in The BMJ journal, examined medical records for nearly 56,000 Danish women between 20. “My coauthor and I are very concerned that the message from this study will be that hormone therapies cause dementia, and that’s not what’s happening here.” “That means women who choose to use hormone therapies may actually be the ones who are already at risk for dementia,” said Kantarci, who cowrote an editorial that was published along with the new study. Kejal Kantarci, a professor of radiology in the division of neuroradiology at the Mayo Clinic in Rochester, Minnesota, who was not involved in the study. Women who have hot flashes, mood or sleep issues - all of which affect cognition - are definitely more likely to seek out and use HRT, said Dr. “An even more convincing (explanation) is that some women were actually prescribed HRT because they had memory problems,” he said in a statement. She was not involved in the study.ĭavid Curtis, an honorary professor at UCL Genetics Institute at University College London, agrees that the link is “biologically implausible.” He was also not involved in the research. That’s biologically implausible,” said Pauline Maki, a professor of psychiatry, psychology, and obstetrics and gynecology and director of women’s mental health research at the University of Illinois at Chicago. “One finding in the study was a link between dementia and the use of HRT for a very short time span, under a year. However, experts who treat and study menopause say the study is unable to draw a direct connection to later-life dementia and that the overall benefits of hormone replacement therapy, or HRT, far outweigh the risks for many patients. Nelsan Pourhadi, a researcher at the Danish Dementia Research Centre at Copenhagen University Hospital Rigshospitalet in Denmark. “The major novel finding of this study is that we observed a persistent, increased rate of dementia for women treated for the short term around the average age of natural menopause, which is about 51 years,” said lead study author Dr. Alzheimer’s and HRT: Study suggests sweet spot to avoid dementia
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